| 33 | Substitution (Tactical) | Charl Holwill for Quinton Davids | Fedsure Western Province |
| 40 | Substitution (Tactical) | Philip Schutte for Graham Carlson | Vodacom Bulldogs |
| 42 | Substitution (Tactical) | Jané Du Toit for Faan Rautenbach | Fedsure Western Province |
| 45 | Substitution (Tactical) | William Devril Boucher for Ryan Hormann | Vodacom Bulldogs |
| 45 | Substitution (Tactical) | Heinrich Kok for Tjaart Coetzee | Vodacom Bulldogs |
| 47 | Substitution (Tactical) | Ryan Pickering for Gregory (Greg) Miller | Vodacom Bulldogs |
| 63 | Substitution (Tactical) | Theodorus Cornelius Erasmus for Andre Fox | Vodacom Bulldogs |
| 63 | Substitution (Tactical) | Tjoepie van den Heever for Paul Saffy | Vodacom Bulldogs |
| 78 | Substitution (Tactical) | JP Nel for Stuart Abbott | Fedsure Western Province |
| 78 | Substitution (Tactical) | Neil de Kock for Wilhelm (Cassie) Carstens | Fedsure Western Province |
| 78 | Substitution (Tactical) | Mark Willard for Adri Badenhorst | Fedsure Western Province |